Bcl9 and Pygo synergise downstream of Apc to effect intestinal neoplasia in FAP mouse models
Descrição
![Bcl9 and Pygo synergise downstream of Apc to effect intestinal neoplasia in FAP mouse models](https://europepmc.org/articles/PMC7564852/bin/cells-09-02125-g004.jpg)
Transcriptional Regulation of Wnt/β-Catenin Pathway in Colorectal
![Bcl9 and Pygo synergise downstream of Apc to effect intestinal neoplasia in FAP mouse models](https://iiif.elifesciences.org/lax/58123%2Felife-58123-resp-fig1-v1.tif/full/full/0/default.jpg)
TBX3 acts as tissue-specific component of the Wnt/β-catenin
![Bcl9 and Pygo synergise downstream of Apc to effect intestinal neoplasia in FAP mouse models](https://crukcambridgecentre.org.uk/sites/default/files/news/pic%20for%20MB%20paper_1.png)
Bcl9 and Pygo synergise downstream of Apc to effect intestinal
![Bcl9 and Pygo synergise downstream of Apc to effect intestinal neoplasia in FAP mouse models](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41388-021-02016-9/MediaObjects/41388_2021_2016_Fig1_HTML.png)
The interactions of Bcl9/Bcl9L with β-catenin and Pygopus promote
![Bcl9 and Pygo synergise downstream of Apc to effect intestinal neoplasia in FAP mouse models](https://iiif.elifesciences.org/lax/58123%2Felife-58123-fig1-figsupp1-v1.tif/full/,1500/0/default.jpg)
TBX3 acts as tissue-specific component of the Wnt/β-catenin
![Bcl9 and Pygo synergise downstream of Apc to effect intestinal neoplasia in FAP mouse models](https://www.biorxiv.org/content/biorxiv/early/2022/06/12/2022.06.10.495115/F3.large.jpg)
β-catenin obstructs γδ T cell immunosurveillance in colon cancer
![Bcl9 and Pygo synergise downstream of Apc to effect intestinal neoplasia in FAP mouse models](https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Fs41467-018-08164-z/MediaObjects/41467_2018_8164_Fig3_HTML.png)
Bcl9 and Pygo synergise downstream of Apc to effect intestinal
![Bcl9 and Pygo synergise downstream of Apc to effect intestinal neoplasia in FAP mouse models](https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Fncomms7380/MediaObjects/41467_2015_Article_BFncomms7380_Fig2_HTML.jpg)
Epsin is required for Dishevelled stability and Wnt signalling
![Bcl9 and Pygo synergise downstream of Apc to effect intestinal neoplasia in FAP mouse models](https://media.springernature.com/w136h75/springer-static/image/art%3A10.1038%2Fs41598-020-59899-z/MediaObjects/41598_2020_59899_Fig1_HTML.png)
Bcl9 and Pygo synergise downstream of Apc to effect intestinal
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