2′-O methylation of the viral mRNA cap evades host restriction by IFIT family members
Descrição
Innate immune restriction and antagonism of viral RNA lacking 2׳-O methylation. - Abstract - Europe PMC
The mRNA cap 2'O methyltransferase CMTR1 regulates the expression of certain interferon-stimulated genes
Structure of human IFIT1 with capped RNA reveals adaptable mRNA binding and mechanisms for sensing N1 and N2 ribose 2′-O methylations
2′-O methylation of the viral mRNA cap evades host restriction by IFIT family members
2'-O-methylation of the second transcribed nucleotide within mRNA 5' cap impacts protein production level in a cell specific manner and contributes to RNA immune evasion
The cap epitranscriptome: Early directions to a complex life as mRNA - Anreiter - 2023 - BioEssays - Wiley Online Library
The broad-spectrum antiviral functions of IFIT and IFITM proteins
2′-O methylation of RNA cap in SARS-CoV-2 captured by serial crystallography
IFIT1: A dual sensor and effector molecule that detects non-2'-O methylated viral RNA and inhibits its translation. - Abstract - Europe PMC
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