Cryo-EM structures show the mechanistic basis of pan-peptidase inhibition by human α2-macroglobulin
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PDF) Structural Mechanics of the Alpha-2-Macroglobulin Transformation
![Cryo-EM structures show the mechanistic basis of pan-peptidase inhibition by human α2-macroglobulin](https://pubs.acs.org/cms/10.1021/acsinfecdis.0c00501/asset/images/medium/id0c00501_0001.gif)
Druggable Hot Spots in the Schistosomiasis Cathepsin B1 Target
![Cryo-EM structures show the mechanistic basis of pan-peptidase inhibition by human α2-macroglobulin](https://www.ebi.ac.uk/pdbe/static/entry/7o7q_deposited_chain_front_image-200x200.png)
PDB 7o7q structure summary ‹ Protein Data Bank in Europe (PDBe
![Cryo-EM structures show the mechanistic basis of pan-peptidase inhibition by human α2-macroglobulin](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41467-021-24651-2/MediaObjects/41467_2021_24651_Fig1_HTML.png)
Structures of ABCG2 under turnover conditions reveal a key step in
![Cryo-EM structures show the mechanistic basis of pan-peptidase inhibition by human α2-macroglobulin](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41467-022-34364-9/MediaObjects/41467_2022_34364_Fig1_HTML.png)
Cryo-EM structures reveal the activation and substrate recognition
![Cryo-EM structures show the mechanistic basis of pan-peptidase inhibition by human α2-macroglobulin](https://europepmc.org/articles/PMC8167298/bin/gr3.jpg)
Structural Investigations of Human A2M Identify a Hollow Native
![Cryo-EM structures show the mechanistic basis of pan-peptidase inhibition by human α2-macroglobulin](https://www.ebi.ac.uk/pdbe/static/entry/7o7l_deposited_chain_side_image-200x200.png)
PDB 7o7l structure summary ‹ Protein Data Bank in Europe (PDBe
![Cryo-EM structures show the mechanistic basis of pan-peptidase inhibition by human α2-macroglobulin](https://www.ebi.ac.uk/pdbe/static/entry/7o7o_deposited_chain_front_image-200x200.png)
PDB 7o7o structure summary ‹ Protein Data Bank in Europe (PDBe
![Cryo-EM structures show the mechanistic basis of pan-peptidase inhibition by human α2-macroglobulin](https://www.researchgate.net/publication/354835133/figure/fig2/AS:1072306491240450@1632669198741/3D-arrangements-of-the-A2Moo-domains-A-Domain-organization-of-A2Moo-B-3D_Q320.jpg)
PDF) Structural Mechanics of the Alpha-2-Macroglobulin Transformation
![Cryo-EM structures show the mechanistic basis of pan-peptidase inhibition by human α2-macroglobulin](https://www.mdpi.com/biophysica/biophysica-03-00041/article_deploy/html/images/biophysica-03-00041-g002-550.jpg)
Biophysica, Free Full-Text
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Recent cryogenic electron microscopy structures of human A2M may
The interaction of alpha 2-macroglobulin with proteinases
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Frozen fresh blood plasma preserves the functionality of native
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