Methodology of the DCCSS later fatigue study: a model to
Descrição
Background A debilitating late effect for childhood cancer survivors (CCS) is cancer-related fatigue (CRF). Little is known about the prevalence and risk factors of fatigue in this population. Here we describe the methodology of the Dutch Childhood Cancer Survivor Late Effect Study on fatigue (DCCSS LATER fatigue study). The aim of the DCCSS LATER fatigue study is to examine the prevalence of and factors associated with CRF, proposing a model which discerns predisposing, triggering, maintaining and moderating factors. Triggering factors are related to the cancer diagnosis and treatment during childhood and are thought to trigger fatigue symptoms. Maintaining factors are daily life- and psychosocial factors which may perpetuate fatigue once triggered. Moderating factors might influence the way fatigue symptoms express in individuals. Predisposing factors already existed before the diagnosis, such as genetic factors, and are thought to increase the vulnerability to develop fatigue. Methodology of the participant inclusion, data collection and planned analyses of the DCCSS LATER fatigue study are presented. Results Data of 1955 CCS and 455 siblings was collected. Analysis of the data is planned and we aim to start reporting the first results in 2022. Conclusion The DCCSS LATER fatigue study will provide information on the epidemiology of CRF and investigate the role of a broad range of associated factors in CCS. Insight in associated factors for fatigue in survivors experiencing severe and persistent fatigue may help identify individuals at risk for developing CRF and may aid in the development of interventions.
BMC Medical Research Methodology 1/2021
Interrupted time series analysis using autoregressive integrated
Clinical evaluation of late outcomes in Dutch childhood cancer
Psychosocial outcomes in long‐term Dutch adult survivors of
PDF) Fatigue trajectories during pediatric ALL therapy are
PDF) Methodology of the DCCSS later fatigue study: a model to
Sebastian NEGGERS, Associate Professor and Researcher
A space-time upscaling technique for modeling high-cycle fatigue
Late adverse effects graded by organ system using Common Toxicity
Flowchart inclusion of CCSs and siblings of CCSs. CCS indicates
Methodology of the DCCSS later fatigue study: a model to
PDF) Questionnaire- and linkage-based outcomes in Dutch childhood
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por adulto (o preço varia de acordo com o tamanho do grupo)
