Local Protein Synthesis and Spine Morphogenesis: Fragile X Syndrome and Beyond

Por um escritor misterioso

Descrição

Behavioral experiences can modulate neural networks through changes in synaptic morphology and number. In contrast, abnormal morphogenesis of dendritic spines is associated with cognitive impairment, as in Fragile X syndrome. Dendritic or synaptic protein synthesis could provide the specificity and speed necessary for spine morphogenesis. Here, we highlight locally translated proteins shown to affect synaptic morphology (e.g., Fragile X mental retardation protein).
Local Protein Synthesis and Spine Morphogenesis: Fragile X Syndrome and  Beyond
Frontiers The Coordination of Local Translation, Membranous
Local Protein Synthesis and Spine Morphogenesis: Fragile X Syndrome and  Beyond
Frontiers Fragile X mental retardation protein is involved in
Local Protein Synthesis and Spine Morphogenesis: Fragile X Syndrome and  Beyond
mRNA Localization: An Orchestration of Assembly, Traffic and
Local Protein Synthesis and Spine Morphogenesis: Fragile X Syndrome and  Beyond
Model showing involvement of FMRP and other FXR proteins (all in
Local Protein Synthesis and Spine Morphogenesis: Fragile X Syndrome and  Beyond
Glial-mediated dysregulation of neurodevelopment in Fragile X
Local Protein Synthesis and Spine Morphogenesis: Fragile X Syndrome and  Beyond
Frontiers Local Translation Across Neural Development: A Focus
Local Protein Synthesis and Spine Morphogenesis: Fragile X Syndrome and  Beyond
Remote Control of Gene Function by Local Translation: Cell
Local Protein Synthesis and Spine Morphogenesis: Fragile X Syndrome and  Beyond
Fragile X syndrome: (What's) lost in translation?
Local Protein Synthesis and Spine Morphogenesis: Fragile X Syndrome and  Beyond
Altered mRNA transport, docking, and protein translation in
Local Protein Synthesis and Spine Morphogenesis: Fragile X Syndrome and  Beyond
Altered mRNA transport, docking, and protein translation in
Local Protein Synthesis and Spine Morphogenesis: Fragile X Syndrome and  Beyond
IJMS, Free Full-Text
Local Protein Synthesis and Spine Morphogenesis: Fragile X Syndrome and  Beyond
A Synaptic Perspective of Fragile X Syndrome and Autism Spectrum
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