Veterinary Sciences, Free Full-Text
Descrição
Canine hemangiosarcoma (HSA) is a relatively common neoplasia, occurring mainly in the skin, spleen, liver and right atrium. Despite the numerous studies investigating the treatment of canine HSA, no significant improvement in survival has been achieved in the last 20 years. Advancements in genetic and molecular profiling presented molecular similarities between canine HSA and human angiosarcoma. It could therefore serve as a valuable model for investigating new and more effective treatments in people and dogs. The most common genetic abnormalities in canine HSA have been found in the phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha (PIK3CA) and neuroblastoma RAS viral oncogene homolog (NRAS) pathways. Mutations are also found in tumor protein p53 (TP53), phosphatase and tensin homolog (PTEN) and cyclin dependent kinase inhibitor 2A (CDKN2A). Known abnormal protein expression could be exploited to trial new target treatments that could be beneficial for both canine and human patients. Despite the high expression of vascular endothelial growth factor (VEGF) and its receptor (VEGFR), no correlation with overall survival time has ever been found. In this review, we explore the most recent developments in molecular profiling in canine HSA and discuss their possible applications in the prognosis and treatment of this fatal disease.
Cypress Veterinary Clinic
Animal Hospital of Mebane
Greenwich Veterinary Center
Surprise Veterinarian Themed Sticker Pack- 20 Pack, For the person who really loves stickers or for a large group. Makes the perfect gift for Vet tech
![Veterinary Sciences, Free Full-Text](https://i.etsystatic.com/26827865/r/il/191640/3663448699/il_fullxfull.3663448699_1f32.jpg)
Surprise Veterinarian Sticker 20-Pack, Mystery Sticker Pack 20ct. ,Vet Student Sticker,Vet Tech Sticker,Laptop Sticker,Water Bottle Sticker
Central - Central Hospital for Veterinary Medicine
![Veterinary Sciences, Free Full-Text](https://i1.rgstatic.net/publication/324768352_Elevated_urinary_excretion_of_free_pyridinoline_in_Friesian_horses_suggests_a_breed-specific_increase_in_collagen_degradation/links/5ae35d61aca272ba507ce868/largepreview.png)
PDF) Elevated urinary excretion of free pyridinoline in Friesian horses suggests a breed-specific increase in collagen degradation
10obongekpe Et Al : Journal of Animal Science and Veterinary Medicine : Free Download, Borrow, and Streaming : Internet Archive
![Veterinary Sciences, Free Full-Text](https://li01.tci-thaijo.org/public/journals/405/article_240036_cover_en_US.jpg)
A Comparison of 3 Anesthetic Agents (MS-222, Benzocaine, and Clove oil) in East Asian Bullfrog (Hoplobatrachus rugulosus)
![Veterinary Sciences, Free Full-Text](http://thevetgazette.com/storage/Screen%20Shot%202021-04-15%20at%2012.08.54%20PM.png?__SQUARESPACE_CACHEVERSION=1618521277636)
SAVMA's The Vet Gazette - Main
de
por adulto (o preço varia de acordo com o tamanho do grupo)