Cells, Free Full-Text
Descrição
Beyond their role in hemostasis, platelets have emerged as key contributors in the immune response; accordingly, the occurrence of thrombocytopenia during sepsis/septic shock is a well-known risk factor of mortality and a marker of disease severity. Recently, some studies elucidated that the response of platelets to infections goes beyond a simple fall in platelets count; indeed, sepsis-induced thrombocytopenia can be associated with—or even anticipated by—several changes, including an altered morphological pattern, receptor expression and aggregation. Of note, alterations in platelet function and morphology can occur even with a normal platelet count and can modify, depending on the nature of the pathogen, the pattern of host response and the severity of the infection. The purpose of this review is to give an overview on the pathophysiological interaction between platelets and pathogens, as well as the clinical consequences of platelet dysregulation. Furthermore, we try to clarify how understanding the nature of platelet dysregulation may help to optimize the therapeutic approach.
Cells, Free Full-Text
![Cells, Free Full-Text](https://www.nejm.org/na101/home/literatum/publisher/mms/journals/content/nejm/2018/nejm_2018.379.issue-5/nejmra1705345/20181209/images/img_medium/nejmra1705345_f1.jpeg)
Sequencing of Circulating Cell-free DNA during Pregnancy
![Cells, Free Full-Text](https://www.cell.com/cms/asset/atypon:cms:attachment:img:d188e6:rev:1697163664447-11289:pii:S2211124723X00096/cover.tif.jpg)
Cells, Free Full-Text
An illustration of the full-duplex cell-free massive MIMO system.
![Cells, Free Full-Text](https://i1.rgstatic.net/publication/328859922_Protein_structural_biology_using_cell-free_platform_from_wheat_germ/links/5be731b192851c6b27b4bc35/largepreview.png)
PDF) Protein structural biology using cell-free platform from wheat germ
![Cells, Free Full-Text](https://www.nejm.org/na101/home/literatum/publisher/mms/journals/content/nejm/2014/nejm_2014.370.issue-26/nejmcibr1404324/20140620/images/img_medium/nejmcibr1404324_f1.jpeg)
Cell-free Fetal DNA — A Trigger for Parturition
![Cells, Free Full-Text](https://www.researchgate.net/publication/336251322/figure/fig1/AS:810118572670976@1570158727784/An-illustration-of-the-full-duplex-cell-free-massive-MIMO-system.png)
An illustration of the full-duplex cell-free massive MIMO system.
![Cells, Free Full-Text](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41467-021-22329-3/MediaObjects/41467_2021_22329_Fig1_HTML.png)
Improving cell-free glycoprotein synthesis by characterizing and enriching native membrane vesicles
![Cells, Free Full-Text](https://ars.els-cdn.com/content/image/1-s2.0-S200103702300185X-ga1.jpg)
Advancing synthetic biology through cell-free protein synthesis - ScienceDirect
![Cells, Free Full-Text](https://media.springernature.com/full/springer-static/image/art%3A10.1186%2Fs12977-018-0434-1/MediaObjects/12977_2018_434_Fig3_HTML.png)
HIV-1 cell-to-cell transmission and broadly neutralizing antibodies, Retrovirology
![Cells, Free Full-Text](https://www.researchgate.net/publication/257300710/figure/fig1/AS:282062016794625@1444260233015/Label-free-full-field-visualization-of-red-blood-cell-RBC-morphology-a.png)
Label-free, full-field visualization of red blood cell (RBC)
Cell-free Macromolecular Synthesis
![Cells, Free Full-Text](https://iiif.elifesciences.org/lax/09771%2Felife-09771-fig3-v3.tif/full/1500,/0/default.jpg)
Rapid cell-free forward engineering of novel genetic ring oscillators
de
por adulto (o preço varia de acordo com o tamanho do grupo)