Cancers, Free Full-Text
Descrição
Imatinib became the standard treatment for chronic myeloid leukemia (CML) about 20 years ago, which was a major breakthrough in stabilizing the pathology and improving the quality of life of patients. However, the emergence of resistance to imatinib and other tyrosine kinase inhibitors leads researchers to characterize new therapeutic targets. Several studies have highlighted the role of histone deacetylase 6 (HDAC6) in various pathologies, including cancer. This protein effectively intervenes in cellular activities by its primarily cytoplasmic localization. In this review, we will discuss the molecular characteristics of the HDAC6 protein, as well as its overexpression in CML leukemic stem cells, which make it a promising therapeutic target for the treatment of CML.
Journal of Cancer Research and Clinical Oncology
![Cancers, Free Full-Text](https://res.cloudinary.com/teepublic/image/private/s--8r3iS75v--/c_crop,x_10,y_10/c_fit,w_992/c_crop,g_north_west,h_827,w_1127,x_-68,y_-82/l_misc:transparent_1260/fl_layer_apply,g_north_west,x_-134,y_-294/c_mfit,g_north_east,u_misc:tapestry-l-s-gradient/e_displace,fl_layer_apply,x_0,y_34/l_upload:v1507037315:production:blanks:uue6kkaylik55suzvwsb/fl_layer_apply,g_north_west,x_0,y_0/b_rgb:000000/c_limit,f_jpg,h_630,q_90,w_630/v1571919157/production/designs/6452735_0.jpg)
I Am Cancer Free! - Cancer Free Gift - Tapestry
An Introduction to Human Cancers
![Cancers, Free Full-Text](https://external-preview.redd.it/06sCBLm7kUvpbJS66BZQkYmlX3iwoIFSjeMHn8V3C64.jpg?auto=webp&s=4bad7696259e6fdab59dcbf297091f0276ee27aa)
Cancers, Free Full-Text
![Cancers, Free Full-Text](https://www.cancer.org/adobe/dynamicmedia/deliver/dm-aid--7831a190-0ef1-478d-bfc3-ac891c891be9/2023-tall-image-facts-and-figures.png?preferwebp=true&quality=82)
Cancer Facts and Statistics
![Cancers, Free Full-Text](https://i1.rgstatic.net/publication/353612591_Late_Stage_Cervical_Cancer_among_Confirmed_Cervical_Cancer_Cases_in_a_Tertiary_Care_Centre_A_Descriptive_Cross-sectional_Study/links/611081951e95fe241abafc65/largepreview.png)
PDF) Late Stage Cervical Cancer among Confirmed Cervical Cancer Cases in a Tertiary Care Centre: A Descriptive Cross-sectional Study
![Cancers, Free Full-Text](https://m.media-amazon.com/images/I/51G1Lh9gqxL._SL10_UR1600,800_CR200,50,1024,512_CLa%7C1024,512%7C51G1Lh9gqxL.jpg%7C0,0,1024,512+67,67,376,376_PJAdblSocialShare-Gradientoverlay-twitter-largeasin-0to60,TopLeft,0,0_PJAdblSocialShare-AudibleLogo-Medium,TopLeft,490,223_OU01_ZBLISTENING%20ON,483,152,55,450,AudibleSansMd,32,255,255,255.jpg)
Cancer-Free, Third Edition by Bill Henderson - Audiobook
![Cancers, Free Full-Text](https://media.springernature.com/lw685/springer-static/image/art%3A10.1186%2Fs13059-022-02710-1/MediaObjects/13059_2022_2710_Figa_HTML.png)
Detecting cell-of-origin and cancer-specific methylation features of cell- free DNA from Nanopore sequencing, Genome Biology
![Cancers, Free Full-Text](https://images.squarespace-cdn.com/content/v1/602801213437442273cae7f8/1615785101361-48KTET8DYNISM9XAV1UR/100+Cancer+Free+sticker.jpg?format=1000w)
100% Cancer Free sticker — Perch Handmade
de
por adulto (o preço varia de acordo com o tamanho do grupo)