BioTech, Free Full-Text
Descrição
(1) Background: The COVID-19 pandemic left many intriguing mysteries. Retrospective vulnerability trends tie as strongly to odd demographics as to exposure profiles, genetics, health, or prior medical history. This article documents the importance of nasal microbiome profiles in distinguishing infection rate trends among differentially affected subgroups. (2) Hypothesis: From a detailed literature survey, microbiome profiling experiments, bioinformatics, and molecular simulations, we propose that specific commensal bacterial species in the Pseudomonadales genus confer protection against SARS-CoV-2 infections by expressing proteases that may interfere with the proteolytic priming of the Spike protein. (3) Evidence: Various reports have found elevated Moraxella fractions in the nasal microbiomes of subpopulations with higher resistance to COVID-19 (e.g., adolescents, COVID-19-resistant children, people with strong dietary diversity, and omnivorous canines) and less abundant ones in vulnerable subsets (the elderly, people with narrower diets, carnivorous cats and foxes), along with bioinformatic evidence that Moraxella bacteria express proteases with notable homology to human TMPRSS2. Simulations suggest that these proteases may proteolyze the SARS-CoV-2 spike protein in a manner that interferes with TMPRSS2 priming.
Does PubMed search full-text? 📑
Download free image of DNA biotechnology science background in
Isothermal, in vitro amplification of nucleic acids by a
Plant Biotechnology Journal: Vol 20, No 1
Where Are the Scientists at Predictive Biotech? - Regenexx Blog
Batch of 50 bags of amino acids Biotech USA eaa zero - Raisin bleu
Free Training Program on Reseach Methodology in Molecular Biology
Journal covers
10 free Magazines from JMBFS.ORG
de
por adulto (o preço varia de acordo com o tamanho do grupo)