Fra-1/AP-1 induces EMT in mammary epithelial cells by modulating Zeb1/2 and TGFβ expression
Descrição
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Epithelial–mesenchymal transition: The history, regulatory mechanism, and cancer therapeutic opportunities - Huang - 2022 - MedComm - Wiley Online Library
![Fra-1/AP-1 induces EMT in mammary epithelial cells by modulating Zeb1/2 and TGFβ expression](https://www.biorxiv.org/content/biorxiv/early/2022/05/11/2020.11.14.383232/F4.large.jpg)
A compromise between Tgfβ and Egfr signaling programs confers the ability to lead heterogeneous collective invasion
![Fra-1/AP-1 induces EMT in mammary epithelial cells by modulating Zeb1/2 and TGFβ expression](https://media.springernature.com/lw685/springer-static/image/art%3A10.1038%2Fs41388-020-1299-z/MediaObjects/41388_2020_1299_Fig6_HTML.png)
TGFβ and EGF signaling orchestrates the AP-1- and p63 transcriptional regulation of breast cancer invasiveness
![Fra-1/AP-1 induces EMT in mammary epithelial cells by modulating Zeb1/2 and TGFβ expression](https://www.biorxiv.org/content/biorxiv/early/2021/06/09/2021.06.08.447526/F2.large.jpg)
Epithelial-mesenchymal plasticity through loss of CTCF motif accessibility and protein expression
![Fra-1/AP-1 induces EMT in mammary epithelial cells by modulating Zeb1/2 and TGFβ expression](https://prod--epp.elifesciences.org/iiif/2/87991%2Fv1%2F383232v5_fig5s1.tif/full/max/0/default.jpg)
The integration of Tgfβ and Egfr signaling programs confers the ability to lead heterogeneous collective invasion
![Fra-1/AP-1 induces EMT in mammary epithelial cells by modulating Zeb1/2 and TGFβ expression](https://www.pnas.org/cms/10.1073/pnas.1613417113/asset/95698439-10a2-4115-aa1e-919aa7c9c856/assets/graphic/pnas.1613417113fig05.jpeg)
Repression of p63 and induction of EMT by mutant Ras in mammary epithelial cells
![Fra-1/AP-1 induces EMT in mammary epithelial cells by modulating Zeb1/2 and TGFβ expression](https://www.science.org/cms/10.1126/sciadv.abf6063/asset/b5dbf587-3999-4aaa-bf59-e6a1cbf369b3/assets/images/large/sciadv.abf6063-f1.jpg)
An EMT–primary cilium–GLIS2 signaling axis regulates mammogenesis and claudin-low breast tumorigenesis
![Fra-1/AP-1 induces EMT in mammary epithelial cells by modulating Zeb1/2 and TGFβ expression](https://media.springernature.com/m685/springer-static/image/art%3A10.1186%2Fs12967-020-02240-z/MediaObjects/12967_2020_2240_Fig3_HTML.png)
Oncogenic functions of the EMT-related transcription factor ZEB1 in breast cancer, Journal of Translational Medicine
![Fra-1/AP-1 induces EMT in mammary epithelial cells by modulating Zeb1/2 and TGFβ expression](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fcdd.2014.157/MediaObjects/41418_2015_Article_BFcdd2014157_Fig1_HTML.jpg)
Fra-1/AP-1 induces EMT in mammary epithelial cells by modulating Zeb1/2 and TGFβ expression
![Fra-1/AP-1 induces EMT in mammary epithelial cells by modulating Zeb1/2 and TGFβ expression](https://www.biorxiv.org/content/biorxiv/early/2021/12/21/2020.11.14.383232/F2.large.jpg)
Inter- and intra-tumor heterogeneity in EMT states confers functional diversity in cells that lead collective invasion
![Fra-1/AP-1 induces EMT in mammary epithelial cells by modulating Zeb1/2 and TGFβ expression](https://pub.mdpi-res.com/ijms/ijms-23-01521/article_deploy/html/images/ijms-23-01521-g004.png?1644316406)
IJMS, Free Full-Text
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Regulation of epithelial-mesenchymal transition by tumor microenvironmental signals and its implication in cancer therapeutics - ScienceDirect
![Fra-1/AP-1 induces EMT in mammary epithelial cells by modulating Zeb1/2 and TGFβ expression](https://media.springernature.com/lw685/springer-static/image/art%3A10.1007%2Fs12272-021-01321-x/MediaObjects/12272_2021_1321_Fig3_HTML.png)
The role of epithelial–mesenchymal transition-regulating transcription factors in anti-cancer drug resistance
![Fra-1/AP-1 induces EMT in mammary epithelial cells by modulating Zeb1/2 and TGFβ expression](https://www.mdpi.com/ijms/ijms-19-03672/article_deploy/html/images/ijms-19-03672-g002-550.jpg)
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